Junping Kou Selected Research

Heart Failure

4/2024	Preventive and Therapeutic Effects of Crocetin in Rats with Heart Failure.
11/2023	Inhibition of OAT1/3 and CMPF uptake attenuates myocardial ischemia-induced chronic heart failure via decreasing fatty acid oxidation and the therapeutic effects of ruscogenin.
1/2023	Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca2+ pathways in heart failure.
10/2022	Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
5/2019	Captopril attenuates TAC-induced heart failure via inhibiting Wnt3a/β-catenin and Jak2/Stat3 pathways.
1/2019	YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways.
8/2017	Extract of Sheng-Mai-San Ameliorates Myocardial Ischemia-Induced Heart Failure by Modulating Ca2+-Calcineurin-Mediated Drp1 Signaling Pathways.
5/2016	Simultaneous Qualitative and Quantitative Analysis of Multiple Chemical Constituents in YiQiFuMai Injection by Ultra-Fast Liquid Chromatography Coupled with Ion Trap Time-of-Flight Mass Spectrometry.

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Junping Kou Research Topics

Disease

18	Inflammation (Inflammations) 01/2022 - 04/2003
13	Cardiovascular Diseases (Cardiovascular Disease) 10/2023 - 03/2011
12	Myocardial Ischemia (Ischemic Heart Diseases) 04/2024 - 11/2016
11	Brain Ischemia (Cerebral Ischemia) 11/2023 - 08/2013
10	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2023 - 08/2013
10	Neoplasms (Cancer) 06/2022 - 09/2011
9	Reperfusion Injury 11/2023 - 10/2014
9	Infarction (Infarctions) 01/2023 - 08/2013
8	Heart Failure 04/2024 - 05/2016
8	Acute Lung Injury 01/2022 - 01/2012
7	Insulin Resistance 10/2022 - 07/2011
6	Ischemia 01/2023 - 08/2013
6	Thrombosis (Thrombus) 02/2020 - 06/2006
5	Edema (Dropsy) 08/2016 - 01/2005
4	Venous Thrombosis (Deep-Vein Thrombosis) 01/2022 - 09/2005
4	Sepsis (Septicemia) 06/2021 - 08/2006
4	Neoplasm Metastasis (Metastasis) 01/2020 - 09/2011
3	Ischemic Stroke 01/2023 - 01/2017
3	Pheochromocytoma 01/2022 - 01/2016
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2022 - 01/2016
3	Hypoxia (Hypoxemia) 01/2019 - 01/2011
3	Pulmonary Edema 08/2016 - 01/2012
2	Hemorrhage 09/2023 - 01/2020
2	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 02/2005
2	Nervous System Diseases (Neurological Disorders) 01/2023 - 01/2017
2	Cerebral Infarction 01/2023 - 01/2017
2	Myocardial Infarction 01/2021 - 04/2020
2	Brain Injuries (Brain Injury) 01/2021 - 01/2021
2	Herpes Zoster 01/2020 - 01/2016
2	Brain Edema (Cerebral Edema) 06/2019 - 01/2016
2	Brain Infarction 06/2019 - 08/2016
2	Fibrosis (Cirrhosis) 05/2019 - 01/2016
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 01/2017
2	Central Nervous System Diseases (CNS Diseases) 01/2017 - 01/2016
2	Dysmenorrhea (Menstrual Pain) 09/2016 - 06/2015

Drug/Important Bio-Agent (IBA)

16	ruscogeninIBA 11/2023 - 07/2005
11	Glucose (Dextrose)FDA LinkGeneric 03/2022 - 01/2016
10	Oxygen (Dioxygen)IBA 03/2022 - 01/2016
10	radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA 01/2022 - 12/2015
8	yi-qi-fu-maiIBA 01/2022 - 01/2016
7	Proteins (Proteins, Gene)FDA Link 09/2023 - 09/2015
7	Neuroprotective AgentsIBA 01/2022 - 10/2014
7	PowdersIBA 01/2020 - 01/2016
6	LipopolysaccharidesIBA 06/2021 - 05/2008
5	Therapeutic UsesIBA 04/2024 - 06/2015
5	blebbistatinIBA 01/2022 - 07/2015
5	Thromboplastin (Tissue Factor)IBA 02/2020 - 03/2011
4	AdipokinesIBA 01/2023 - 11/2014
4	ginsenoside Rb1IBA 03/2022 - 12/2015
4	Myosin Type IIIBA 01/2022 - 01/2017
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2020 - 09/2005
4	CytokinesIBA 02/2020 - 07/2011
4	SaponinsIBA 01/2020 - 09/2011
4	Xylenes (Xylene)IBA 05/2008 - 04/2003
4	CarrageenanIBA 05/2008 - 07/2005
3	CateninsIBA 01/2022 - 05/2019
3	schizandrinIBA 01/2021 - 12/2015
3	Hematoxylin (Haematoxylon)IBA 01/2021 - 05/2019
3	Evans Blue (Blue, Evans)FDA Link 01/2021 - 01/2016
3	Eosine Yellowish-(YS) (Eosin)IBA 01/2021 - 05/2019
3	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2021 - 07/2015
3	Insulin (Novolin)FDA Link 03/2016 - 07/2011
3	DiosgeninIBA 01/2016 - 08/2012
3	ophiopogonin DIBA 07/2015 - 07/2005
3	danggui-shaoyao-sanIBA 06/2015 - 02/2005
3	Analgesics (Analgesic Drugs)IBA 01/2014 - 01/2005
3	Acetic Acid (Vinegar)FDA LinkGeneric 05/2008 - 01/2005
2	Fatty Acids (Saturated Fatty Acids)IBA 11/2023 - 05/2019
2	Small Interfering RNA (siRNA)IBA 10/2023 - 01/2016
2	ginsenoside RdIBA 10/2023 - 01/2023
2	Myosin Light Chains (Myosin Essential Light Chain)IBA 09/2023 - 01/2020
2	Dasatinib (BMS 354825)FDA Link 09/2023 - 01/2020
2	GlutaminaseIBA 06/2022 - 01/2021
2	Coloring Agents (Dyes)IBA 01/2021 - 01/2005
2	triphenyltetrazoliumIBA 01/2021 - 01/2021
2	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 01/2020
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 04/2020 - 12/2016
2	Creatine Kinase (Creatine Phosphokinase)IBA 04/2020 - 12/2016
2	Particulate MatterIBA 12/2019 - 12/2018
2	GinsenosidesIBA 08/2019 - 05/2019
2	LipidsIBA 08/2019 - 05/2019
2	Palmitic Acid (Hexadecanoic Acid)IBA 05/2019 - 01/2016
2	Dynamins (Dynamin)IBA 01/2019 - 01/2017
2	Nonmuscle Myosin Type IIAIBA 11/2018 - 01/2016
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 05/2008
2	Adenosine Triphosphate (ATP)IBA 01/2017 - 01/2016
2	InflammasomesIBA 08/2016 - 09/2015
2	Biomarkers (Surrogate Marker)IBA 05/2016 - 04/2016
2	QuercetinIBA 03/2016 - 12/2014
2	Sirtuin 1IBA 01/2016 - 11/2014
2	PalmitatesIBA 08/2012 - 05/2012
2	Ethanol (Ethyl Alcohol)IBA 05/2008 - 09/2005
2	Histamine (Histamine Dihydrochloride)FDA Link 09/2006 - 04/2003
1	trans-sodium crocetinate (crocetin)IBA 04/2024

Therapy/Procedure

13	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 08/2006
7	Oral Administration 08/2016 - 09/2005
6	Ligation 04/2024 - 09/2005
5	Therapeutics 06/2022 - 01/2012
3	Intravenous Injections 08/2016 - 01/2012
2	Ischemic Postconditioning 12/2021 - 11/2016